Small changes are fine when you've tweaking a system that you understand that is close to where you want it.
Sadly, little about Neocron is in that state right now (amusingly, pre 2.2, while much worse for being single-class dominated, was probably much fewer tweaks from something farier). Instead, we've got systems that don't work like they are supposed to, or acheive exactly the opposite to what they are supposed to, and numbers that are miles out (you yourself mentioned laser beam cannons outdamaging semi-auto pistols by 200-300%. Small tweaks won't cut it.)
Also, the more that I look at the numbers and setup, the more convinced I am that a "balanced" APU in terms of damage/resists will plunge us back into monk-o-cron, if nothing else is changed..