I had quite a few issues at first.
Full uninstall of everything NC related. Cleaned everything with a reg cleaner to make sure nothing was left.
Fresh download of the client. Let it install EVERYTHING (All the DX9 redists, etc.)
Restart as it asks.
It will install the launcher, download the game, then "update image" for a while.
HOWEVER, Even when launching, I remain having an issue. It continually tells me that there is no disc in the drive and to insert one. If I mash "Continue" approximately 10 times, it will launch the game and quit complaining.
https://i.imgur.com/mEVWLmT.jpg
Windows 7.
Edit:
Not just in the launcher. Even after the game has launched, the game will continue to complain that there is no disk in the drive and force an alt-tab of the game to desktop to see the message.