I know its still to early to talk about this, but I was concerned about running such old game like neocron in brand new operating system. I have installed Win10 Technical Preview on my second partition to check if NC (and other games) will run fine.
Everything work very good, just needed to install VC redist and log in.
I didnt notice any bigger difference between performace of nc under win 7 or 10, but seems that on 10 everything runs a bit more smoother.
Just one note: NC installed before on win 7 but on other partition, didnt want to work (window immediately closed), I needed to make clean install.